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HP1 recognition of the H3K9 methyl mark and interactions between the H3K9 methyltransferase Su var)3-9 and HP1 are thought to enable spreading of heterochromatin over significant distances and to explain the existence of vast heterochromatic territories at centromeres.
Cells were plated overnight on type I fibrillar collagen-coated (1 mg/mL) (Chou et al., 1996) glass coverslips (MatTek dishes; Ashland, MA) to enable spreading and formation of focal adhesions.
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In the Atlantic Ocean, gray seals (Halichoerus grypus) are vectors of PDV that enable spread of disease to harbor seal populations and provide contact between North Sea and Arctic Ocean species (12 ).
We thus have a reasonable understanding of what types of molecular variation enable a flu virus to escape prevailing immunity, although this advantage by itself is not sufficient to enable spread in the human population.
It also enables spreading code design with no restrictions on the number of users or code length.
With this in mind, a careful selection of co‐scheduled users that lie in orthogonal subspaces can reduce the interference level and improve the spectral efficiency by enabling spreading code reuse.
Transcriptional silencing by TEL has been proposed to involve oligomerization of its N-terminal SAM domain, building a proteinaceous core around which the DNA is wrapped, thereby enabling spreading of the repressor activity [50].
Moreover, the IR6 protein facilitates egress of viral capsids from nuclei of infected cells and enables spread of the viral protein between adjacent cells independently of virus infection [ 15].
The detached S. aureus cells will have an activated quorum-sensing system that leads to the secretion of numerous invasive factors, enabling spread through the host tissues and the development of an infection.
Overall, identifying the DNA features enabling spread or escape from inactivation will be an important contribution to understanding long-range gene regulation.
There is no factual evidence either that size was the problem - indeed large universal banks enable the spreading of risk both across geographies and product lines.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com