Exact(2)
RILs possess several advantages over F2 or BC1 populations for mapping genes and quantitative trait loci (QTL), and high levels of homozygosity and recombination in the RILs enable replicate studies across different environments by different research groups.
For these organisms it would be necessary to use alternative (non-F2) population structures such as RILs that enable replicate homozygous recombinant genotypes and therefore allow both destructive sampling to obtain DNA and simultaneous phenotype analysis within each line.
Similar(58)
The preferred mapping populations were recombinant inbred lines (RILs) or doubled haploid populations because the fixed nature of these lines enabled replicate measurements.
Genome-wide scans with an Affymetrix high-density single-nucleotide polymorphism (SNP) microarray enabled replicate comparisons of pools of different molecular forms, in three separate populations.
This strict approach enables replicating the study and extending it in the future if new evidence becomes available.
Subsequent research by others focused on telomerase, an enzyme that might possibly be used to enable cells to replicate well beyond what had become known as the Hayflick Limit.
My dream for the future would be to have three times the people we have now at work — say 20,000 just in eastern Africa and to enable people to replicate business models on their own.
FPGAs enable us to replicate any application with very acceptable results, although the development time is higher.
A good methods section would ideally enable anyone to replicate it.
These properties enable Brucella to replicate without generating obvious cell damage, a characteristic that may be essential for establishing long lasting chronic infections.
In contrast, IFN-γ treated Perforin-2 −/− MEFs enable MRSA to replicate.
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