However, the water-mediated NOE approach introduced in this study should represent a further complimentary approach to enable interrogation of systems involving reversible binding in the fast exchange regime.
Helicobacter organisms warrant consideration as potential pathogenic entities in UC. Isolation of these organisms from colonic tissue is needed to enable interrogation of pathogenicity against established criteria.
Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation.
The proposed methodology eliminates the need for knowledge of prior stress histories and enables interrogation of system state using the identified damage pre-cursors.
Thirdly, as flow cytometry, which enables interrogation of individual cells with multiple parameters, is employed in the assay, only a selected population of cells in the samples, e.g., CD8+ and live T cells, can be included in data analysis and thus interpretation of assay results and identification of false positives are facilitated.
The Illumina Genome Analyzer (GA), originally by Solexa, enables interrogation of mRNA expression via the mRNA Sequencing protocol.
High-throughput sequencing of cDNA (RNA-Seq) does not rely on prior knowledge, enabling interrogation of all transcripts including potentially novel transcripts uncaptured in Sanger-based sequencing [ 8].
The Methylation450K array uses 2 different probe types with unique chemistries enabling interrogation of both high and low density CpG regions in the genome.
The use of WGST, therefore, provides the highest degree of phylogenetic and genotyping robustness by enabling interrogation of all possible informative SNPs along with other genetic variation (e.g., insertions, deletions, gene changes).
The first stage involved linear time history analysis carried out using SAP 2000 to verify the response of the complete framing system and its ability to restore global frame stability and to enable iterative interrogations.
