Sentence examples for enable fate from inspiring English sources

How the robust pluripotency program is dissolved to enable fate transition is less appreciated.

However, it is still largely unknown how small molecules activate the endogenous gene regulation network, and gradually enable cell fate transitions.

The direct reprogramming from fibroblasts to functional neurons enables cell fate conversion to cover an even wider area including differentiation, de-differentiation, and trans-differentiation (Vierbuchen et al., 2010).

The offspring of the labelled cells inherit the reporter expression, enabling their fate to be tracked over time.

This study highlights subcellular compartmentalization of cell-state regulators as a means of enabling cell-fate transition.

Our previous studies demonstrated that Hdac1 promotes expression of proneural genes, represses Notch target gene expression and enables neural fate-determining responses to Hedgehog pathway activity [ 9, 12].

Prolonged propagation of hNPs shifted their differentiation potential from neuronal to glial fate, enabling them to differentiate into astrocytes and oligodendrocytes, [4].

In addition, this model system enables tracking the fate of developing β-cells in response to various stimuli.

This protein plays a pivotal role by enabling binary cell fate specification events to occur as a result of its asymmetric sequestration in post-mitotic neurons [ 28, 88, 90], How Numb exert its inhibitory function on Notch signalling remains poorly understood.

Quantification of natural and engineered carbon nanotubes (CNT) in the environment is urgently needed to study their occurrence and fate and to enable a proper risk assessment.

The addition of the Rho-associated kinase inhibitor [20] prior to and during the sorting procedure enable the analysis of the fate of single cells by a colony formation assay.