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These results enable elucidation of the mechanisms driving aggregate formation (and thus C sequestration in microaggregates and silt plus clay fractions) in topsoil and subsoil.
Structural information about useful enzymes would enable the generation of new enzymes exhibiting high activity, enhanced stability, and altered-coenzyme specificity, and would also enable elucidation of the detailed reaction mechanisms and substrate-binding specificities.
This study represents a comprehensive analysis of MBT substrate specificity, establishing a foundation for the rational design of selective MBT domain inhibitors that may enable elucidation of their role in human biology and disease.
Recently, new methods have been developed that enable elucidation of the biologic pathways of tumors, yielding additional information about the metabolism of the tumor tissue.
Finally, this review provides recommendations for future studies that would enable elucidation of the role of diet and microbiota and how these factors may be (inter)related in the pathophysiology of IBS.
Study 1 in this work had a cross-sectional design; therefore, it did not enable elucidation of the causal relationships between serum levels of AGEs and vascular inflammation in humans.
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The importance of cholangiocytes in liver function and disease has been elucidated through the development of animal and cell-based models that have enabled elucidation of their role in the progression of liver disease (Glaser et al., 2009; Strazzabosco and Fabris, 2008).
Identification of the estrogen receptor β (ERβ) and research into various ligand classes has enabled elucidation of molecular aspects important in selective ER binding.
Quantification of the nanostructural changes taking place during the formation of geopolymer binders (up to 128 days) enables elucidation of the impact of mix design parameters on the resulting aluminosilicate gel nanostructure.
In addition, the proposed criterion is scale-independent, which enables elucidation of the nature of various types of instability in arbitrary ferroelectric systems so that complicated instability issues in practical situations can be addressed.
This enables elucidation of critical interactions and gaining knowledge and understanding that supports innovative solutions by balancing resource supply and demand and increasing synergies between components, while maintaining ecosystems.
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