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A simple feasibility check, to determine whether a fixed number of available clusters will enable a trial to detect a required difference at required power, therefore consists of evaluating whether the following inequality holds: (21) for equal cluster sizes [ 2], and (22) for unequal cluster sizes.
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But the UN-appointed international judges have warned that if agreement cannot be reached on a framework to enable a fair trial that meets the highest standards, they will pull out.
The main objective of a pilot trial is to provide sufficient assurance to enable a larger definitive trial to be undertaken.
The larger number of volunteers in the 50 mcg cohort was designed to yield sufficient interested volunteers to enable a malaria challenge trial after the third vaccination.
An oval shaped stream-gutter (6.0*4.0*0.8 m; 6,000-l) was constructed to enable a 3-months swimming trial.
After the trial stimulus (and the break), the 1 second-break and the fixation cross were again presented (to enable a break between the trials and as a warning for the next stimulus, respectively).
The trials were made possible by the assistance of Masimo Corporation who provided modified oximeters to enable a masked comparison between the trial groups.
In this way only 12%% of the available cases did not support the forecasting procedure; 13,991 cases enabled a first-trial treatment, 3,035 required a second e 333 a third with a progressive loosening of the criteria.
The protesters' chief complaint today was legislation that would enable a defendant in a criminal trial to claim that a judge was biased and appeal for a change in venue.
Detailed economic data will be collected throughout the trial to enable a comprehensive evaluation of the intervention's efficiency when compared to routine care.
There are limited data on the effectiveness of GCSF-induced stem cell mobilisation in patients with cirrhosis, so this trial will enable a more detailed assessment of the safety and efficacy of achieving this.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com