Sentence examples for emulated trials from inspiring English sources

We constructed 131 emulated trials using THIN, pooled the data from all trials, and followed patients until occurrence of diabetes, death, or administrative end of follow-up, whichever occurred earlier.

Briefly, we generated a set of emulated trials in which the first trial recruited participants for the duration of the first month of the study (in this study, January 2000).

Instead, they attempt to emulate randomized trials by exploiting inherit characteristics of the observational data.

To emulate three target trials: single treatment vs. no treatment, joint treatment vs. no treatment, and head-to-head comparison of two treatments, we explain how to estimate the observational analogs of intention-to-treat and per-protocol effects, using hazard ratios and survival curves.

One approach to causal inference with observational data emulates randomized trials by using an instrumental variable (IV), a variable that influences exposure but, conditional on the exposure, has no influence on the outcome (Angrist, Imbens, and Rubin, 1996).

Many analyses of observational data are attempts to emulate a target trial.

The trial's pragmatic approach emulated the usual delivery of assessment and care with healing outcomes confirmed by an individual blinded to study arm.

The design of the study emulated that of a 'phase III' clinical trial in that the addition of the 'intervention' was compared with an 'optimised background' or 'standard of care' control condition.

We emulated the design and analysis of a hypothetical randomized trial of statins, estimated the observational analog of the intention-to-treat effect, and adjusted for differential survival bias using inverse-probability weighting.

Elinor Barker has emulated Welsh compatriot Nicole Cooke by winning women's junior time-trial gold at the World Road Championships in the Netherlands.

The CDX-1307 phase II trial offered a novel combination of vaccine therapy and chemotherapy, and such a treatment regimen can be emulated in future studies.