Although we lack experimental evidence that allows us to state whether GSTP1 retains GST activity when bound by HPV-16 E7, it is remarkable how closely the conformation of this complex emulates the pattern of intermolecular contacts in the GSTP1 homodimer.
Early research focused on adapting existing hardware to emulate the pattern recognition capabilities of living organisms.
Consistent with the model, gain-of-function experiments with these constructs suggested that progressive changes in the level of Gli activity were sufficient to emulate the patterning activity of graded Shh signalling (Stamataki et al, 2005).
They made glass targets, tied feathers to them and trappers sent them into the air from different angles and speeds to emulate the flight patterns of birds.
Usually my, like, advice-manifesto is to emulate the behavioral patterns of rich old white men.
"But it could be argued," his biographer Anthony Cronin writes, "that in [O'Brien's] case, he was, in time, destroyed by its opposite, by a too ready acceptance of the necessity of emulating the life pattern of the majority who do not have a special vocation and are not burdened by the claims of art".
Flann O'Brien, born 100 years ago on 5 October, had a proper job and took his family responsibilities seriously – though as Anthony Cronin points out in his biography No Laughing Matter, in the end he was destroyed by them, "by a too ready acceptance of the necessity of emulating the life pattern of the majority who do not have a special vocation".
To overcome this problem we used electroporation conditions for transfecting scattered cells with high levels of Delta-1 expression, emulating the endogenous pattern of expression.
This flow pattern and flow dynamics were then used to calibrate a CFD model that emulated the flow pattern of the liquid fuel across an inclined concrete road surface.
