In order to assess the influence of gastric emptying on gallbladder dynamics, the postprandial gallbladder motility in subjects with normal or abnormal gastric emptying was also compared in SSc patients and dyspeptic controls.
Gallbladder emptying was considered abnormal if half-emptying time was greater than 35 minutes (mean + 2 SD in healthy controls) [ 25, 26].
Interestingly, although the gallbladder emptying was similar in subjects with or without altered gastric emptying, an altered gallbladder refilling was only found in SSc patients with delayed gastric emptying.
This was not the case, however, of dyspeptic controls, who showed similar gallbladder emptying and refilling curves accompanied with normal or impaired gastric emptying.
Estrogen increases cholesterol in the bile, and progesterone slows the emptying of the gallbladder.
Objective: The objective was to test the hypothesis that continuous enteral feeding impairs gallbladder emptying in infants.
Background & Aims: The mechanisms responsible for the abnormalities of gallbladder emptying in patients with chronic acalculous gallbladder disease (AGD) have not been elucidated.
In health, endogenous cholecystokinin (CCK) stimulates gallbladder emptying.
Gallbladder dysmotility has been implicated as a putative mechanism underlying acute acalculous cholecystitis and lipid malabsorption in the critically ill, despite nutrient-stimulated gallbladder emptying never having been quantified in this population.
However, at variance with the gallbladder emptying, the gallbladder refilling has been shown to be altered in both SSc patients and dyspeptic controls.
