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We employed previously established network science methodologies to construct a genetic interaction network and characterize epistatic interactions within this network [ 18, 19].
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An ideal chemopreventive agent should be highly effective at multiple sites, orally consumable, minimally toxic or non-toxic, and should employ previously established mechanisms of action [ 38].
The final part, written by Tavarekere Nagaraja, will be devoted to the last seventeen years of Fenstermacher's work during which he and his colleagues validated modern technologies such as magnetic resonance imaging (MRI) by concurrently employing previously established radioisotopic techniques.
Employing previously established biomarkers and biomarker patterns as classifiers [ 19, 20], we investigated if a therapeutic benefit of Irbesartan in microalbuminuric type 2 diabetes patients can by displayed by proteomic changes in urine.
We will use previously established scoping methodology.
To quantitatively analyze the protein composition of the immature 30S subunits isolated under high salt condition, we employed a previously established QMS method (Guo et al., 2013).
We employed a previously established gene set enrichment analysis algorithm (Genomica; [ 23]) to identify miRNA target sites enriched in mRNAs up-regulated after miR-128 transfection.
To further characterize global MEK1/2/ERK1/2-induced MEK1/2/ERK1/2-inducedosphorylation within human RBchangesemployed a previnusly established label-free quantitative proteinphosphorylationtegy to the plasma membrane ghosts of human RBCs [ 18, 34].
To test this possibility, we employed a previously established transgenic system to determine the transcriptional regulatory activities of the three WRKY proteins through assays of a reporter gene in stably transformed plants [ 15].
We used laser tweezers for measuring the rupture forces, employing a previously established assay (Dewenter et al., 2015).
We employed MDA/RLN2 stable transfectants previously established in our laboratory and shown to produce the 18 kDa pro-RLN2.
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