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D-optimal mixture design was employed for the optimization of aforesaid CMAs and evaluated for in vitro dissolution, globule size, ex vivo permeation studies as the critical quality attributes (CQAs).
The Taguchi methodology was employed for the optimization.
The new developed model is employed for the optimization purposes.
Response surface methodology (RS M was employed for the optimization of the immobilized xylanase activity.
Response Surface Methodology involving Box-Behnken Design was employed for the optimization of process parameters viz.
A Box Behnken design was employed for the optimization of yerba mate extraction.
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Section 3 details the inverse problem and iterative technique we employ for the optimization problem.
After screening of various components (type of gelators, organic and aqueous phase) and construction of phase diagrams, a D-optimal mixture design was employed for the systematic optimization of the LO composition.
An OA8 (27) matrix was employed for the SFE optimization.
A mixed level OAD matrix, OA16 (41 × 212) was employed for the initial optimization.
The construction of a Box Behnken design model was employed for the systematic optimization of the ECH composition.
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