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We were delighted to find that 1-bromonaphthalene could also be employed (entry 2).
To our delight, the desired succinimide 3 a could be formed in 53 % yield with 99%% ee and excellent diastereoselectivity when the precatalyst 4 d was employed (entry 4).
Although the desired coupling did not take place when n-butanol was employed (entry 3), we found that the use of t-amyl alcohol gave the aminated product in good yield (entry 4).
The desired sulfinate was only observed in significant quantities when sodium formate in isopropyl alcohol was employed (entry 1).[ 19] The use of calcium formate provided a small improvement in efficiency (entries 2 and 3), and these conditions were then used to evaluate a number of alternative phosphine ligands (entries 4 9).
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Ito and Lee [4] find little evidence that FSCs employ entry deterrence strategies.
Another issue for regional airlines like Colgan is that they tend to employ entry-level airline pilots.
Nested I employed identical entry criteria at the initiation of therapy with either MTX or a TNF inhibitor.
The majority was young adults (39.1, SD = 9.4) years old, educated and economically active (79.2% had more than 9 years of education, and 77.1% were employed at entry).
Oink's heavily trafficked user forums revealed a community that resembled Ellis himself: technically literate middle-class twentysomethings, mostly male, enrolled in university or employed in entry-level jobs.
The employed PDB entries were the most suitable ones of several crystal structures available for protein kinase A because of their similarity to the compounds contained in MUV548.
The FIM I2 x) for the nonredundant set of TDOA measurements is employed, with entries defined as: I 2 ( x ) = - E ∂ 2 ln p ( r i ; x ) ∂ x ∂ x T = ∂ μ i ∂ x T C i - 1 ∂ μ i ∂ x, (78).
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