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There were 27 colonized patients that empirically received linezolid or daptomycin and two of the four that could be de-escalated were de-escalated.
There were eight non-colonized patients who empirically received linezolid or daptomycin, and two of the three patients that could be de-escalated were de-escalated.
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Today, no factor predictive for efficiency of third-generation regimens has been validated, and all node-positive patients empirically receive adjuvant regimens based on anthracycline and taxane [ 3], although the optimal role for taxanes in this setting remains controversial.
In these circumstances, participants still received empirically based tobacco cessation support at the time of need.
At admission, the patients received empirically administrated broad-spectrum antibiotics; ceftazidime or piperacillin-tazobactam.
Colonoscopy findings were normal; because of evidence of leukocytes in the feces and elevated fecal fat level, however, he received empirically prescribed metronidazole.
Third, the protocol aimed for IVR-triggered counselling calls to focus on the specific risk factor(s) identified by the IVR assessment; all participants received empirically based support at the time of need, but not all calls were focused on the identified risk factor(s).
In this study, the exclusion of patients who only received vancomycin empirically did not change the association between appropriate empiric therapy and mortality.
It is difficult to empirically quantify the education received by an individual, especially when the focus is on analyzing its quality beyond the years of education.
When we excluded patients who only received vancomycin empirically (n = 305), we found a similar association between receipt of appropriate empiric therapy and mortality (adjusted HR: 1.03; 95% CI: 0.53, 1.97).
One patient received fluconazole empirically, which was changed in the course to amphotericin B [ 22].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com