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We analyzed 3′ end triplets of PCR primer sequences obtained from refereed journal articles, to test those recommendations and to make empirical recommendations for primer design.
Examples of applications are presented with special regard to event tree analysis, rock mass classifications, and reliability-based design of tunnels by means of the empirical recommendations of rock mass classifications.
The comparison of the results with the NBCC 2015 (National Building Code of Canada) provisions for NSCs shows that these empirical recommendations typically underestimate the seismic demands on NSCs.
Examining more thoroughly the bottom area of Fig. 5, it can be seen that SSD provision adequacy is provided at the area where the crest vertical transition falls entirely inside the horizontal curve area, thus confirming, but even more expanding on divided roads, empirical recommendations addressed by current design guidelines [1, 4].
Based on such knowledge, empirical recommendations may be customized.
Ideally, data should be derived from large samples reflective of the region for which the empirical recommendations apply.
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The WHO's empirical treatment recommendations for septicaemia is chloramphenicol and/or benzylpenicillin [ 10, 11].
There is an ongoing demand for local surveillance of sepsis aetiology and monitoring of empirical treatment recommendations.
Aggregate data on invasive infections and anticipated patterns of antimicrobial resistance can provide useful local epidemiological data to inform and validate empirical management recommendations.
In addition, when it comes to reducing the risk of caries within populations, or groups of patients within a practice, we have, in general, provided empirical standardized recommendations, such as "brush and floss" and "use fluoride toothpaste".
The study concludes with the discussions of theoretical and empirical implications and recommendations for future research.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com