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Archival research, based on self-created or commercial databases, is the dominant empirical method in financial accounting.
The first one is called empirical method, in which a site-survey is needed to create a signal database.
Given the limitations of a modeling approach for assessing the estrogenic activity of complex mixtures of chemicals, it is valuable to consider other methods such as the empirical method in which the biological effects of the mixture are evaluated as a single entity.
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