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The use of adult learning principles, such as active involvement from the residents in the learning process and presenting material at the time when the residents are engaged in the issue, have been emphasized in the revised curriculum.
This important point is emphasized in the revised Discussion.
Authors' response: As we have explicitly emphasized in the revised manuscript, the model structures might be all wrong, they are just theoretical predictions that await experimental scrutiny.
Authors' response: indeed, the absence of detectable capsid proteins in Pandoraviruses is most intriguing and is emphasized in the revised manuscript.
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The model is deliberately oversimplified to allow straightforward conclusions on the relationships between the standard code and various random codes, and we emphasize this in the revised Discussion.
This has been emphasized in the Discussion section of the revised manuscript.
We have more strongly emphasized this point in the revised text.
We have emphasized this point in the revised manuscript and the reason for us to choose 40nm as the target radius is based on DNA polymer model is now described in the text.
To avoid confusion and also to incorporate the comments below, we have modified the title to, "Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant" and emphasized "light/dark cycles" in the revised manuscript.
We emphasize this point in the revised manuscript.
We have emphasized this effect size in the revised manuscript, and also updated Figure 3 to show additional microscopy fields.
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