Authors' response: indeed, the absence of detectable capsid proteins in Pandoraviruses is most intriguing and is emphasized in the revised manuscript.
In the journal article, Dr. Neil T. Moynihan and his co-authors emphasized that in the absence of the above "red flags," "extensive testing, including the routine use of blood tests, stool studies, and imaging is not required".
It must be emphasized that in the absence of a gold standard for the clinical studies, it is challenging to draw general conclusions with respect to the relevance of MAR in the clinical setting.
This was further emphasized by the absence of detectable changes in p62 levels when analyzed by immunoblot after starvation across wild type and mutant fibroblasts or in levels of LAMP1, a marker for the lysosomes (Supplemental Fig. 1).
IRB members in Botswana emphasized the absence of trust as a significant problem, attributing this in part to lack of understanding on the part of Batswana and lack of adequate explanation and study feedback on the part of researchers.
One analyst emphasized that the "absence of evidence is not necessarily evidence of absence," and that administration officials still believed that they might eventually find incriminating samples.
The president of the European Commission, José Manuel Barroso, emphasized that even in the absence of a formal arrangement, Russia and Ukraine had to settle their problems without threatening gas supplies and leaving Europeans freezing during the winter.
NICE recommends CSII therapy where achievement of optimal glycaemic control has been precluded by disabling hypoglycaemia but has emphasized the absence of studies in high-risk individuals together with the need for randomized control trials to assess biomedical and psychosocial outcomes of both analogue MDI and CSII in those with established SH [ 34].
Land Rover emphasized the absence of bumper-height regulations in persuading Judge Jan A. Pluim of the Los Angeles Superior Court earlier this year to dismiss the lawsuit filed against it by Diane Y . Diaz de Veer who suffered brain injuries when her Saab was hit by a Range Rover.
These findings emphasize that even in the absence of infarcts, Cx43 gap junction distribution becomes heterogeneous in disease.
