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Altogether, our results emphasize a role for Fyn activation to restrain the inhibitory potential of Erk1/2 on PPARγ Ser-84, therefore allowing a maximal response of PPARγ to ghrelin.
Our results emphasize a role of CREB in stress-regulated gene expression and support the view that the therapeutic actions of antidepressants are mediated via CRE/CREB-directed transcription.
Other theories of rostral prefrontal cortex also emphasize a role of this region in the processing of particular sources of information.
Studies in rodents, using experimentally induced peripheral inflammation, emphasize a role for pro-inflammatory cytokines in mediating the production of sickness behaviors (6,9).
While the loss of both LGI1 alleles by somatic mutations in glioma cell lines was first thought to contribute to malignant brain tumours (Chernova et al., 1998), our findings emphasize a role in epileptogenesis.
While most group foraging theory focuses on the role of grouping relative to "patch finding rates" [ 5, 6, 8- 14] 14], our results emphasize a role of grouping relative to "staying in a patch" in order to better deplete a patch.
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Some authors have emphasized a role for sustainable intensification in closing global 'yield gaps' between the currently realized and potentially achievable yields.
Consistent with this characterization, investigations into the biological function of bNOS have also emphasized a role for NOS-dependent nitrate and nitrite production in aerobic and microaerobic respiration.
This mechanism emphasizes a role of timing control in achieving robust pattern scaling and provides a new perspective in examining the phenomenon in natural systems.
Interestingly, accumulating data have emphasized a role of IGF-1 activated Akt in phosphorylation and nuclear localization of Mdm2 [40] [42].
Some studies emphasized a role of microtubules in intracellular transport of activated GR into the nucleus [15], [16].
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