Treatment of the cells with TRAIL alone had little effect on Mcl-1 expression levels, emphasising the requirement for Mcl-1 downregulation in the execution of apoptosis, even in the presence of caspase-3 activation.
Compared to the ITER reference design, the test stand emphasises the requirement of flexibility, which is necessary during the development of the gyrotron.
This study emphasises the requirement for randomised studies of nutritional intervention initially in patients with NSCLC.
The Calman-Hine report (1995) emphasised the requirement for the provision of palliative care throughout cancer care: 'there should be a smooth progression of [palliative] care between home, hospital and hospice' (p 16).
This emphasises the requirement to study BGB allocation patterns, though the anchorage of open grown trees and of those grown in the woods may be different.
This process evaluation has emphasised the requirement for both improved liaison and the development of systems for review as core functions of chronic disease management.
"Plainly, it again emphasises the requirement for a balance to be drawn between the urgent need of the intelligence agencies to safeguard the public and the protection of an individual's privacy and/or freedom of expression.
19 We explained the operation of the device to the physicians and their staff, emphasising the requirement that the patient should be left alone during five readings.
He emphasises that in the Netherlands the requirement of a fair trial is also a central part of the quality of claim assessment.
Continuing reports of an association between FFP administration and adverse patient outcomes in patients, including the critically ill, further emphasise the requirement to improve the evidence base, especially for transfusion of FFP to nonbleeding patients [ 6, 9- 13, 32- 35].
