Sentence examples for emphasis trial from inspiring English sources

The EMPHASIS trial (European Thoracic Oncology Platform) compares treatment of erlotinib vs docetaxel in patients with squamous histology in patients who failed first-line chemotherapy.

To systematically review published randomized controlled trials (RCTs) evaluating pharmacological and non-pharmacological therapies in patients with hand osteoarthritis (OA), with an emphasis on trial methodology.

Officials of Mr. Obama's legal team have met several times with the chairman of the bar association panel over the last year to raise concerns over the number of negative ratings, and have raised the possibility that the panel's emphasis on trial experience may have a disparate impact on female and minority lawyers because they may have been less likely to become litigators.

The costs for other CV hospitalisations, adverse events and devices were based on the proportion of patients from the EMPHASIS-HF trial experiencing each subcategory of event.

Quality of life was calculated using the utility formula from Göhler et al 14 using the baseline characteristics of the patients in the EMPHASIS-HF trial.

Second, as the EMPHASIS-HF trial was stopped early, due to early benefit in the eplerenone-treated group compared with the standard care arm, there is some uncertainty regarding the long-term outcomes of eplerenone in the available clinical data.

Based upon the EMPHASIS-HF trial, this modelling analysis shows that the use of eplerenone in patients with HF-REF and mild symptoms reduced hospitalisations (particularly HF hospitalisations) and the costs associated with these.

Results from the EMPHASIS-HF trial were used to develop a discrete-event simulation model estimating lifetime direct costs and effects (life years and quality-adjusted life years (QALYs) gained) of the addition of eplerenone to standard care among patients with chronic systolic HF and mild symptoms.

MRA treatment extension to patients with mild-to-moderate HFrEF as a consequence of the results of the EMPHASIS-HF trial (Eplerenone in Mild Patients Hospitalization and Survival Study in HF) [ 21], which enrolled 2737 patients aged ≥55 years with New York Heart Association (NYHA) functional class II symptoms and an ejection fraction (EF) <30% (<35% if the QRS duration was >130 ms).

Trial design that incorporates additional emphasis on communications between trial staff and trial participants may require a multistep process.

This article breaks down the elements of designing clinical trials, with an emphasis on randomized controlled trials, as applied to advancing natural orifice translumenal endoscopic surgery research.