The occurrence of emesis in each group was compared after a mean dose of 27 Gray.
The patients who were treated by verum or sham experienced close to 50% lower occurrence of emesis compared to the patients receiving standard care.
For paediatric patients undergoing PDA ligation, postoperative analgesia with continuous infusion epidural via caudal approach produced shorter ICU stay, less occurrence of postoperative emesis, earlier oral intake, elimination of intravenous opioid supplementation, and shorter hospital stay compared with single injection caudal epidural techniques.
Treatment arm was the only determinant factor for the occurrence of delayed emesis (P = 0.0101).
This pilot study with a limited number of patients showed that the 1-, 2-, or 3-day palonosetron dosing cohorts were not statistically different from each other for the occurrence of no emesis (primary end point) throughout the cumulative 7-day study period.
Alternatively, patients were interviewed at each visit, regarding the occurrence of nausea and emesis and use of rescue medication, with responses recorded (C2007-01).
Young and co-workers found that emesis questions per se increased self-reported occurrence of nausea [34].
A prospective randomised trial was conducted to compare the efficacy and toxicity of granisetron, dexamethasone plus prochlorperazine with granisetron alone in controlling cisplatin-induced delayed emesis and to identify the important factors that influence its occurrence and severity.
4 It should be noted that the strongest predictor of delayed CINV is the occurrence of symptoms in the acute phase, but delayed emesis arises in the absence of acute symptoms in 18% to 24% of patients.
In patients receiving cisplatin who were followed up throughout repeat chemotherapy cycles, not only the incidence of delayed vomiting in the second/third cycles depended on the protection against emesis achieved in the acute phase of the same cycles, but also the occurrence of delayed vomiting was a predictor of acute emesis in the subsequent cycles of chemotherapy.
A 5-Month-Old Boy With Postprandial Emesis.
