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This review summarizes emerging observations from studies of cell biology, preclinical animal studies, and preliminary clinical trials and describes the findings of investigations on this topic to develop an initial blueprint of the mechanisms by which DHEA slows OA progression.
Emerging observations indicate that the epithelial-to-mesenchymal transition (EMT) is associated with tumor progression and the generation of cells with cancer stem cells (CSCs) properties.
Additionally, some chemokines might also act as organ-specific angiogenesis modulators, accordingly with emerging observations on the existence of organ-specific molecules regulating vessel formation [ 18].
Moreover, emerging observations suggest that synaptic plasticity underlies all brain functions, including the physiological regulation of energy homoeostasis, and that impaired synaptic constellation and plasticity may lead to pathological development and conditions.
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Specifically, we will address the recent evidence that TLRs elicit both protective and detrimental effects in atherosclerosis and the emerging observation that the outcome of TLR signaling is dependent on the agonist and responding cell type.
Another emerging observation is that ubiquitin ligases could both activate or inhibit gene expression, depending on the context of the transcription complex [ 13].
An emerging observation from this analysis is that optimal delivery of PHC services depends on the strength and nature of relations among all health systems actors.
One emerging observation is that biglycan and fibromodulin are preferential substrates for MMP-13, whereas degradation of decorin and lumican is much less effective.
Indeed, one emerging observation in both extracellular signal- regulated kinase 1 and 2 (ERK1/2) and mammalian target of rapamycin (mTOR) signaling is the realization that pathways generate specific biological responses dependent upon where in the cell the signal originates [ 12].
More candidates for binary asteroids are emerging from observations of the pulsating brightness of asteroids that pass near Earth.
Due to the nature of the transportation critical infrastructure and its monitoring using WSN, there is a real hazard of fluctuation of the analyzed network traffic parameters, i.e., possibility of emerging outlying observations (outliers).
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CEO of Professional Science Editing for Scientists @ prosciediting.com