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Angiolillo, D. J. & Ferreiro, J. L. Antiplatelet and anticoagulant therapy for atherothrombotic disease: the role of current and emerging agents.
We analyze emerging agents that are already producing significant results in different models of human cancers, including MCL.
Other important novel or emerging agents include the histone deacetylase inhibitors; a novel antifolate, pralatrexate; the proteasome inhibitor bortezomib; and the purine nucleoside phosphorylase inhibitor forodesine.
High placebo response rates and the ethics of testing emerging agents against placebo in an era of effective therapies are challenges to traditional randomized controlled trials.
These emerging agents with diverse mechanisms of action have demonstrated promising anti-tumor activity in patients with relapsed/refractory MM, and rationally designed combinations with established agents are being investigated in the clinic.
While the addition of these new treatment options is a great advance for men with metastatic CRPC, there are many new questions arising regarding sequencing of these treatments with each other, with previously existing therapies, and with the emerging agents now in clinical trials.
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Boras, then a young and emerging agent, also described McDonald as a unique talent, and even threatened to jump to a rumored third major league.
In this paper, we review the software agent technology applications in communications with more emphasis on mobile agents since it is an emerging agent technology.
Dr. Tokarz identified and characterized the first defined cluster of one such virus, enterovirus D68, an emerging agent implicated in a severe outbreak of pediatric respiratory disease in the US in 2014.
Recent advances in the object-oriented paradigm and the emerging agent-oriented paradigm gave promise to the development of such mechanism for inter-object communication that was difficult to achieve previously.
Therefore, even if a novel emerging agent would differ markedly from all known sequences, as was the case for the novel 2003 coronavirus [14], [15], it could be possible to detect it with precision.
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