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While genomics can be used on samples before and after drug resistance emerges to identify the likely associated mutations, most of the known mutations and genes associated with drug resistance were discovered by analyzing a priori candidates such as drug target genes or genes located on plasmids.
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However, to date, no established method has emerged to identify effective shRNAs, which have lower intracellular abundance than transfected siRNAs and undergo additional processing steps.
Due in part to the shared experience, albeit under French dominance, various justifications emerged to identify "Germany" as a single state.
Massive methods like high-density oligonucleotide probe arrays have recently emerged to identify single feature polymorphisms (SFPs) as attractive alternatives to SNPs [ 17].
An emerging scope to identify novel cis-acting elements and elements acting in tandem may possibly lead to unraveling the complex web pattern for salinity signaling.
One key methodology, fragment-based virtual screening (FBVS) or fragment-based drug discovery (FBDD), is an emerging area to identify novel, small molecules for preclinical studies.
The main goals of the investigation were to evaluate the emerging technologies, to identify the most promising products, and to anticipate the scientific and societal inputs that will influence the evolution of the medical device industry.
The task that remains is to use current and emerging markers to identify optimal biological subsets for new therapeutic agents.
We undertook a literature review of this emerging indication to identify evidence within orthopaedic surgery and other surgical disciplines.
Interview transcripts and field notes were merged and analysed by emerging themes to identify a coding frame.
To facilitate a phase-out process, alternatives assessment is commonly applied as an emerging approach to identifying chemicals (or materials, processes, and behavior changes) serving as substitutes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com