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Several emergency workers at the plant were exposed to doses in excess of the emergency dose limit of 250 millisieverts, but no-one has exceeded a dose of 1Sv (1000 mSv).
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HSE said the notices did not indicate an immediate risk from legionella, as this was being controlled by the emergency dosing of chemicals and Macfarlan Smith's subsequent voluntary shutdown of cooling towers.
Nevertheless, in May the government ordered 5 million emergency doses of BioThrax for civilians.
Emergency doses are replenished as needed.
DAART participants were also supplied with three days of "emergency doses" to use if they did not attend the OTP as scheduled.
The overall medical emergency team dose was 56/1000 admissions.
TBI management recorded included use of bolus mannitol in the emergency room (dose of 1 g/kg), therapeutic hypothermia (target temperature and duration of therapy), and use of neuromuscular blockers.
However, when using the iv route in emergency, higher doses of NAC (6000 mg) may be necessary to obtain a preventive effect as tested by Marenzi and collegues [ 17].
To achieve a more rapid effect in an emergency, a bolus dose of flecainide can be administered as a slow injection of 1 2 mg/kg over 10 min, or in divided doses, up to a maximum of 150 mg, while monitoring blood pressure.
Without sufficient stockpiles of yellow fever vaccine, Brazil is examining another emergency option: fractional dosing, or administering one-fifth of the recommended dose of yellow fever vaccine.
In the emergency setting, probabilistic dosing may be considered.
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