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The emergence of plasma creatinine in the predictive model is not surprising because renal impairment is a predictor of poor outcome in non-paced patients with heart failure.
The presence of a minority subclone harbouring KRAS mutations within tumours might explain the secondary resistance to anti-EGFR therapy (Tougeron et al, 2013) and the emergence of plasma KRAS mutations (Diaz et al, 2012).
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Previously, Arnulf et al. [ 8] reported that the prevalence of monoclonal gammopathy was high in patients with primary hyperparathyroidism compared to general population and that high PTH levels might facilitate the emergence of a plasma cell clone.
The preferential bone marrow location of Gaucher disease and multiple myeloma suggests that multiple bone marrow alterations induced by Gaucher cells may create microenvironments that could favour emergence of a plasma cell clone.
For these reasons, we assessed the emergence of radiometabolites in monkey plasma following intravenous administration of [C] 7– 9.
By transmission electron microscopy (TEM), the damaged cells exhibited loss of plasma membrane integrity and emergence of intracellular vacuoles.
We have used the term AKT 'translocation' to indicate emergence of (cytosolic) AKT in the plasma membrane in response to growth factors.
We are aware that environmental ROS might not offer the complete explanation and that other still unknown factors contributed to the emergence of the ER from the plasma membrane.
The emergence of circulating/exosomal miRNAs in the plasma of patients with colon cancers has thus used as biomarkers [ 34].
Extensive exploration of the operational window of the ITER divertor has lead to the emergence of simple scalings of the divertor plasma parameters with input power and plasma density, which are used here to make an educated guess on the divertor performance in a commercial reactor.
However, the emergence of these turbulence regimes is related to the enhancement of plasma density irregularities and to the development of the Kelvin–Helmoholtz instability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com