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The lens plate is formed in the 4 mm embryonal stage.
We chose E16.5 embryos because this embryonal stage coincides with the onset of secondary myogenesis.
Both alleles are embryonal lethal at embryonal stage 16, with embryos failing to produce head and ventral cuticle [53], [55].
In adult mice, we observed a biallelic expression of the gene in all the postnatal and adult stages analyzed; however, we found a monoallelic maternal expression in the cerebellum at the embryonal stage E17.5.
Cadps2 gene expression performed in mice at different developmental stages was biallelic in the postnatal and adult stages; however, a monoallelic (maternal) expression was detected in the embryonal stage, suggesting that CADPS2 is subjected to tissue- and temporal-specific regulation in human and mice.
Similar(55)
The endocannabinoid system (ECS) including its receptors, endogenous ligands ("endocannabinoids"), synthesizing and degradating enzymes, and transporter molecules has been detected from the earliest embryonal stages and throughout pre‐ and postnatal development; endocannabinoids, notably 2‐arachidonoylglycerol, are also present in maternal milk.
In embryonal stages, GABA mediates Cl− effluxes in neuronal and non-neuronal tissues [23].
p53 and SIRT1 both influence development, for example during embryonal stages and in neuronal tissues [6], [8], [16] [18], where RNA splicing also has a central role [34], [74].
As with crosses to alleles of Fak56D and Src42A, the point of lethality was at the time of dorsal closure, at embryonal stages 15 16, and associated with defective cuticle formation.
Without the guidance from the mature bone marrow niche, the erythrogenesis was recapitulating the embryonal stages.
Recapitulation of primitive as well as advanced embryonal stages of vasculature formation followed co-implantation of avascular (in vitro cultured) N202 breast tumor spheroids and homologous tissue grafts into mouse dorsal skin chambers.
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