Moreover, these reports pointed out that only KGDH heterozygosity permits normal embryonal development in consequence of residual KGDH activity.
The embryonic stem cell is an almost mythically powerful and versatile human cell, fleetingly present during the earliest days of embryonal development.
To study the impact of in vitro maturation (IVM) on embryonal development with the use of time-lapse imaging.
The family of GLI zinc finger transcription factors regulates the expression of genes involved in many important cellular processes, notably embryonal development and cellular differentiation.
For Liang et al. the use of abnormal fertilized zygotes underscores the absence of any intention to explore further embryonal development in vitro or in vivo, thereby at least formally avoiding some of the ethics controversies.
EMT remains a controversial pathobiological model in the clinical setting, and some question the validity of the concept outside of the confines of in vitro conditions and embryonal development [37].
Moreover, Xenopus embryo analysis in this study also uncovered a role for USP15 in embryonal development in vivo, dependent on its effect on TGF-β superfamily signaling (Inui et al., 2011).
Loss of Dcas had limited effect on embryonal development.
Due to the fundamental requirement of VEGF-A in embryonal development it has been impossible to create viable knockout models for VEGF-A.
This work identifies a strong interaction between the Dcas, and integrin pathway genes, including integrins and their effector kinases Fak56D and Src42A, during early embryonal development in Drosophila.
