Some scrambling was observed for the free peptide; however, almost no scrambling occurred in the amide hydrogens of the peptide backbone embedded in the membrane.
Beyond this polarity difference, the community found that the designed binding surfaces were, on average, structurally less embedded in the designed monomers, suggesting that backbone conformational rigidity at the designed surface is important for realization of the designed function.
Despite its low hydrophobicity, the P56S major sperm protein (MSP) domain becomes largely embedded in the membrane environment with high backbone rigidity.
Astonishingly, the P56S MSP domain is mostly embedded in the membrane environment with high backbone rigidity, and is composed of five well-formed helices at N- and C-ends linked by a long unstructured loop.
Owing to the hydrogen bonding interaction of –COOH in AA on the network backbones with –NH2 and –OH in ICs embedded in the crosslinked network, the composite hydrogels are different from those without ICs in their swelling and degradation behaviors.
Both the backbone amide and carbonyl of Val interact with the hydrogen bond donor and acceptor nitrogen atoms embedded in the central aminothiazole core, consistent with the binding mode observed for PIK-93 bound to p110γ [ 30].
"He is absolutely embedded in the game.
Cooking is embedded in the Henderson culture.
But embedded in the narrative are clues.
He is deeply embedded in the culture.
