Sentence examples for embedded in genomic from inspiring English sources

High heterogeneity in cancer has been evident since early studies, and approaches to reveal such heterogeneity embedded in genomic profiling data are showing promising results.

This promoted increased alkali and RNase H2 sensitivity, leading us to conclude that ribonucleotides that are embedded in genomic DNA are most likely the consequence of misincorporation by DNA polymerases.

In the majority of cases these neighborhoods were embedded in genomic regions, which are hot spots for integration of several other mobile elements and restriction-modification operons and are potentially associated with negatively supercoiled DNA [Additional file 1].

vCGH was constructed on HMMs to capture two primary sources of uncertainty embedded in genomic data: the significant but subtle correlations between GEP and CGH, and the sequential transitions of CNAs along a chromosome.

In this paper, HMM was first time used for an integrative analysis of the GEP-to-CGH prediction which intended to capture two primary sources of uncertainty embedded in genomic data: (1) the significant but subtle correlations between GEP and CGH; (2) the sequential transitions of DNA CNAs along a chromosome.

RNase H2 null embryos accumulate large numbers of single (or di-) ribonucleotides embedded in their genomic DNA (>1,000,000 per cell), resulting in genome instability and a p53-dependent DNA-damage response.

Finally, several bacterial TEs were found embedded in larger genomic fragments transferred horizontally from bacterial endosymbionts to their eukaryotic hosts (Dunning Hotopp 2011).

Using the dual-luciferase reporter (DLR) assay, we identified 10 (43%) erythroid-specific enhancers embedded in the genomic regions of KLF1, KLF6, KLF9, and KLF13.

While most research addressing protoplast fusion focuses on traits embedded in the genomic DNA, mitochondrial transfer without karyogamy occurs at a much higher frequency.

However, the phylogenetic signal embedded in the genomic abundances of these very old FFs, which contain domains of all ages in their make-up (the 'modern effect' sensu [ 27]), is strong and dissects the appearance of the three superkingdoms.

The Fit gene cluster in the genome of Pf-5 is embedded in a large genomic region, with features indicative of horizontal acquisition, such as phage-related proteins and unusual nucleotide composition (Fig.  3a) [ 17].