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For example, if your project will need 180 sections on an electron microscope (EM), it would be a little silly to try requesting funds on the grant to buy an EM.
EM: It is.
EM It was "only" £4.50 a pint in hospitality tents (so I was reliably informed).
EM: It's entirely fear.
EM: It's not so much the marriage.
EM: It's useful to think in terms of a 50-year timetable.
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In cryo-EM, it is nevertheless a requirement that one makes very thin films, which have extremely high values of the surface-to-volume ratio.
one captures with immuno-EM, it is possible to see individual vesicles or vesicles/tubules in clusters.
In addition, with the recent advancements in electron detector development and image processing methods in cryo-EM, it may soon be possible to generate tomographic volumes with sub-nanometer resolution routinely (Schur et al., 2013).
By immuno-EM, it was shown that at the limiting membrane of the early endosomal vacuole the GHR and EGFR are concentrated in flat, bilayered coated areas with a fuzzy outer layer of clathrin and a dense inner layer of unknown protein composition.
EM: Yes, it was cathartic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com