The molecular water transporter remained elusive until discovery of the Escherichia coli water channel, AqpZ, however the regulation of the aqpZ gene expression and physiological function of the AqpZ protein are unknown.
What awaits them is a nation still mostly untrammelled by tourists, where, in the remoter parts, it's still quite possible to grasp that elusive feeling of discovery.
Paleontologists have long classified Alioramus within the superfamily Tyrannosauroidea, but because its remains were for many years poorly known, a more precise classification had remained elusive until the discovery of A. altai.
However, the molecular mechanisms controlling these events remain elusive despite its discovery a long time ago.
The mechanisms underlying the progressive neurodegeneration in PD are still elusive and the discovery of the active or main driving force is of paramount importance in the search of effective therapeutic strategies.
The NAADP-activated Ca2+-release channel remained elusive until the discovery of a novel family of endolysosomal-specific membrane proteins designated the TPCs (two-pore channels) which share similarities with voltage-gated Ca2+ channels [ 20, 21].
The development of alternative strategies to non-invasively monitored BBB function has been elusive, until the recent discovery of CSF and glial proteins present in plasma when the BBB is breached [22] [25].
A critical and so far elusive milestone is the discovery of a stable and immunogenic conformational epitope of the HIV envelope that would elicit broadly reactive neutralizing antibodies against primary isolates of HIV (9 ).
However, a predictive biomarker for oncrasin compounds remained elusive until our recent discovery that such compounds require the expression of a sulfotransferase (SULT), SULT1A1, in cancer cells for their anticancer activity and that the expression of SULT1A1 is capable of predicting the responses to oncrasin compounds [ 195].
Is the quest for a physical thing or is it for something more elusive – meaning, purpose, self-discovery?
