Thus, although EGFR plays important roles in tumorigenesis, cancer cells are genetically unstable and can elude the effect of EGFR-targeted therapy through several well-characterized and some not-yet-known resistance mechanisms.
The virus very high mutation rate is capable of eluding the effects of competitive inhibition based drugs in a very short time [6].
Herbivorous insects use complex protease complements to process plant proteins, useful to adjust their digestive functions to the plant diet and to elude the antidigestive effects of dietary protease inhibitors.
Endodormancy contributes to elude the detrimental effects of the low temperatures in winter by preventing the resumption of growth under non-optimal conditions for survival.
To elude the confounding effects of reduced hyperlipidemia on the eplerenone-treated ZDF myocardium, we tested the apoptosis response in eplerenone-pretreated cultured cardiomyocytes exposed to high concentrations of a saturated fatty acid (HF) and/or glucose (HG).
For drug screening and validation, a less cytotoxic and highly sensitive reporter gene that faithfully reflects the drug effectiveness and eludes the cytotoxic effect of reporter gene product is required.
To elude the cameras, I stepped out of the mosque.
Can Walt elude the DEA forever?
The Uzans may elude the grasp of Motorola and Nokia.
Moreover, the use of BoxA appears to allow a more efficient HMGB1 targeting while eluding the known gastrointestinal side effects of ASA.
