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As a chemical elucidation tool, X-ray diffraction of compound (10) revealed the geometry and conformation of this class compounds.
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By integrating innovative mode-of-action-based biodiagnostic tools including in vitro and in vivo tests, transgenic organisms, and 'omics' techniques with powerful fractionation and cutting edge, analytical, and computational structure elucidation tools, powerful new EDA approaches are being developed for the identification of toxicants in European surface and drinking waters.
By integrating innovative mode-of-action-based biodiagnostic tools including in vitro tests, transgenic organisms and "omics" techniques with powerful fractionation and cutting edge analytical and computational structure elucidation tools, a new generation of effect directed analysis (EDA) approaches will be developed for the identification of toxicants in European surface and drinking waters.
There is a clear advantage of elucidating with a software tool over attempting an elucidation by hand as this ensures that every potential isomer is assessed.
The superposition of the ligands was performed with the tool Pharmacophore Elucidation (MOE-package), which takes all conformations of the ligands into account.
RNAi has emerged as an essential laboratory tool for elucidation of gene function and has rapidly been adopted for functional genomics, pathway analysis and target validation.
Enzymatic digestion is a useful tool for elucidation of structural information and for quantitating polysaccharides and oligosaccharides [ 11].
From the twelfth century onwards, there was much discussion of the logic of syncategoremata, and exposition (expositio), i.e., interpretive analysis, became one of the main tools of elucidation.
Mass spectrometry (MS) has emerged as one of the premier tools for elucidation of lipid A structures.
Raman spectroscopy is a useful tool for the elucidation of bioinorganic mechanisms.
Network re-engineering may serve as a useful tool in the elucidation and discovery of phosphorylation regulatory mechanisms as well as in the validation of observed cellular phenotypes.
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