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The popularity of the challenge attracted the attention of a new group of chemists, specifically Ph.D. students, seeking out answers to structure elucidation problems that could be included into their thesis.
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The difficulty of a structure elucidation problem depends more on the type of the investigated molecule than on its size.
In this study, we convert this structural elucidation problem to a formal mathematic formula and refer to the problem as the Chemical Substituents-Core Chemical Substituents-CoreChemical Substituents-Core
Hence the difficulty of the structure elucidation problem depends more on the type of the investigated molecule than on its size.
Hence the difficulty of the structure elucidation problem depends more on the type of the investigated molecule than on its size [1].
The actual difficulty of the structure elucidation problem depends more on the type of the investigated molecule than on its size.
Given that every human expert in structure elucidation will be biased by his or her own education, history of certain compound classes worked on, or types of spectroscopy used, CASE systems can be incredibly valuable by suggesting solutions to the structure elucidation problem outside of our range of experience.
These issues collectively constitute the "structure elucidation problem," which has dogged combinatorial synthesis since its inception.
The promise of exploiting combinatorial synthesis for small molecule discovery remains unfulfilled due primarily to the "structure elucidation problem": the back-end mass spectrometric analysis that significantly restricts one-bead-one-compound (OBOC) library complexity.
Drug substance punch face interactions were reported in the first of the articles in this series, and focused on the elucidation of adhesion problems in tablet compression.
Morphology was studied because it was the material believed to be the most favorable for the elucidation of the problems of evolution, and we all thought that in embryology the quintessence of morphological truth was most palpably presented.
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CEO of Professional Science Editing for Scientists @ prosciediting.com