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An exploration of common rules (property motifs) in amino acid sequences has been required for the design of novel sequences and elucidation of the interactions between molecules controlled by the structural or physical environment.
Although mechanisms of trastuzumab resistance have been described, a complete understanding of these pathways requires elucidation of the interactions within and between their members.
Further elucidation of the interactions between different glutamate genes and their relationships with such structural, functional brain substrates will enhance our understanding of the link between dysregulated glutamatergic neurotransmission and neuroimaging endophenotypes in BD.
Further elucidation of the interactions between the epithelial and stromal elements of the developing breast and the susceptibility of these interactions to environmental factors is a key focus for BCERC investigators.
Further elucidation of the interactions between different glutamate genes and their relationships with these structural, functional, and chemical brain substrates will enhance our understanding of dysregulated glutamatergic neurotransmission and its relation to neuroimaging endophenotypes in BD.
A combination study of chlorogenic acid with the drug cisplatin [ cis-diamminedichloroplatinum II)] was cis-diamminedichloroplatinum IIlysis and possible elucidation of the interactions in Artemisia tea extract.
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However, a clear elucidation of the interaction between the antimicrobial substances and the other host components implicated in tissue formation would certainly contribute to the identification of the optimal solutions.
Elucidation of the interaction of GTP with the C-terminal cluster of MoaA resulted from elegant ENDOR studies of the C24/28/31S MoaA complexed with [N or N]-5′-GTP and [N]-5′-ITP.
Future work is going to be devoted to further calibration of the thresholding step in a data-adaptive way, and to tune it to a better elucidation of the interaction-expression interplay.
Nowadays, many efforts are being made towards the elucidation of these interactions in order to develop better treatments to many diseases and malfunctions, especially cancer progression.
Future studies should aim at the elucidation of the molecular interactions of cMYC and HDAC2, such as protein-protein interactions, feedback loops, and non-histone lysine deacetylation, governing the susceptibility of MYC amplified MB to HDACi.
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