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Because of this finding, the alignment provides a robust starting point for homology modeling of the permeation paths of other K+-selective channel classes and elucidation of sequence-function relationships therein.
The elucidation of sequence variants in CB4856 has occurred in several steps.
The elucidation of their precise function for TLT function will need further work.
While the number of newly sequenced genomes and genes is constantly increasing, elucidation of their function still is a laborious and time-consuming task.
Shimamoto, K. Glutamate transporter blockers for elucidation of the function of excitatory neurotransmission systems.
Cozzetto, D. & Jones, D. T. The contribution of intrinsic disorder prediction to the elucidation of protein function.
The major roadblock to elucidation of the function of these unique molecules has been the lack of any identifiable phenotypes for mutants unable to make msDNA.
The elucidation of σM function and finding σM-controlled promoters needs further investigation.
Elucidation of the function(s) for each human protein-encoding gene has been a prominent challenge in biomedical research after the completed deciphering of the sequence of the human genome.
Our results provide the first step towards elucidation of the function of the family of classical PTPs.
Elucidation of the function of these smRNAs would largely depend on recognition of their target molecules.
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