These include, for example, the elucidation of protein protein relations in terms of ligand or cavity topological similarity via quantitative measures and the prediction of unreported potential ligand-target interactions by detecting potentially cross-binding ligands.
The elucidation of folding kinetics in terms of the different role exerted by amino acid residues on the basis of their topological characterization is of the utmost importance for applicative studies as demonstrated by Stanley and coworkers [20] for the elucidation of amyloid peptide oligomerization process.
In this review we discuss how metabolomics has contributed so far to characterizing TB, with emphasis on the resulting improved elucidation of M. tuberculosis in terms of (1) metabolism, (2) growth and replication, (3) pathogenicity, and (4) drug resistance, from the perspective of systems biology.
The precise biological substrates that underpin cognitive reserve require further elucidation but can be considered in terms of those associated with neurodevelopment (e.g. white matter integrity [ 5]) and those associated cognitive ageing (inflammation, oxidative stress and apoptosis) [ 6].
The right wing is bound to parse it as an unprecedented call to promote abortion in the United States, but the content of Barack Obama's commencement speech at Notre Dame was in fact far from revelatory in terms of offering elucidation of his own views on abortion.
Expansion factors were determined for further elucidation of the effect of crosslinking in terms of coil volume change.
The synergistic interaction between humans and computers can be highly beneficial in terms of less biased approaches to elucidation as well as dramatic improvements in speed and throughput.
Future studies will focus on the elucidation of the mechanism of metabolite deregulation and its consequences in terms of disease progression and treatment options.
Scalar spin spin (J) coupling provides valuable information for molecular structure elucidation, but the multiplet structure it causes is very expensive in terms of spectral resolution.
First, it provides a comprehensive elucidation of the genetic control mechanisms for a complex trait or disease in terms of traditionally defined additive and dominant effects, newly defined imprinted effects, and their interactions.
