New York performances by William Christie and his brilliant early-music ensemble, Les Arts Florissants, have long been dependable sources not only of historical elucidation but also of vibrant entertainment.
This structural elucidation will also enable a better identification of the epitope regions for the development of specific binders to the 35 kDa antigen.
In any case, the findings of Boerner et al. suggest that chromosomes have many new mysteries awaiting future elucidation and also challenge researchers to develop increasingly innovative and sophisticated approaches for this purpose.
Most current methods of mechanism elucidation are also unable to account for or convey changes in mechanism (ie primary and secondary targets) with changes in structure.
These efforts will facilitate not only isolation of improved strains but also elucidation and identification of new genetic targets for use in strain improvement programs.
While the most evident application of the technique proposed in this paper is the direct measurement of one bond scalar 13C 1H couplings for structural elucidation purposes, it also offers interesting potentialities for measuring 13C isotopic enrichments in metabolic samples.
For example, a TA focused on the development of a training system may require not only characterization of the correct way of performing the targeted tasks, but also elucidation of optimal ways for teaching correct task performance, including identification of common mistakes, helpful hints and cues, and appropriate assessment and feedback techniques.
The possible underlying pathogenetic mechanisms need also elucidation.
Also, the elucidation of the importance of humoral immune defenses against intracellular pathogens constitutes a priority to improve the rational design of new vaccines.
Structural information about useful enzymes would enable the generation of new enzymes exhibiting high activity, enhanced stability, and altered-coenzyme specificity, and would also enable elucidation of the detailed reaction mechanisms and substrate-binding specificities.
