Molecular markers have a great impact on elucidating the biological variance within tumors, they allow new and more accurate classifications and they have the potential to improve diagnosis, estimation of prognosis and treatment decisions in individual patients [ 3- 6].
Recently, gene expression analysis was shown to elucidate the biological variance between tumors and molecular markers were identified that led to new classification systems that provided better prognostic and predictive parameters.
In order to elucidate the biological variance between normal ovarian surface epithelial (NOSE) and epithelial ovarian cancer (EOC) cells, and to build a molecular classifier to discover new markers distinguishing these cells, we analysed gene expression patterns of 65 primary cultures of these tissues by oligonucleotide microarray.
The underlying genetic and developmental architecture that leads to variance between males in sperm morphology are largely unknown but represent a key area of research in elucidating the evolution of complex morphological phenotypes.
To elucidate the contribution of the variance to the pathogenesis of disease, expression variances were tested in SM samples of RA patients, osteoarthritis (OA) patients, and normal controls (NCs).
Further behavioral genetic analyses are needed to elucidate the cause of behavioral variance associated with Disc1 L100P strain.
The most intense signals were integrated, and the variances were calculated for each integral, in order to elucidate the inter-individual variation for the cloned and control pigs.
To further elucidate the general nature of the mechanisms controlling variance, we turned off diffusion and analyzed the circuit in individual nuclei using ideas from dynamical systems theory.
Thus, the distribution of z-scores can also be used as a proxy to elucidate the level of sex bias expression, with the advantage over variance ratios that is directly interpretable in biological terms.
Thinking about water waves helps to elucidate the solution.
She is working to elucidate the mechanisms underlying antidepressant efficacy.
