Sentence examples for elucidating the functional consequences from inspiring English sources
This study investigated the microanatomical response to compression of intact and degenerate cartilage-on-bone samples with the aim of elucidating the functional consequences of articular surface disruption and related matrix changes.
Indeed, the transformative and paradigmatic discoveries in this exciting field lie in elucidating the functional consequences of these oxidative cysteine modifications in physiological and pathological processes.
Moreover, elucidating the functional consequences of these mutations will provide the opportunity to study FMRP domains by identifying critical residues and characterizing the function of different domains in a clinically relevant context, as demonstrated by the I304N point mutation.
Theoretically, reconstruction of the molecular interaction networks linked to gwas-genes by systems biology approaches may help to elucidate the functional consequences related to each susceptibility allele and the combined effects of more genetic variants.
Nevertheless, further studies are needed to elucidate the functional consequences of damped circadian rhythms in each peripheral organ.
It will be of interest to identify the actual causal variants and to elucidate the functional consequences of these variants.
Studying the genetics of gene expression is a tool that can help elucidate the functional consequences of GWAS variants.
Next, we wanted to elucidate the functional consequences of interfering with mTOR signaling for PDGF-BB-mediated cellular responses, i.e. survival, migration and proliferation.
Muscle mitochondria from the knockout mouse show decreased proton leak (Brand et al., 2005), which might explain these observations, but does not necessarily elucidate the functional consequences of pathological mutations.
More work is needed to elucidate the functional consequences and impact of high copy-number repeats (for example, long interspersed nuclear elements), and of rare CNVs on clinical phenotypes, such as CD.
To elucidate the functional consequence of the haplotype T/A variation of hMYH, we constructed the recombinant cDNA with mutations, expressed them in cultured cos-7 cells and checked the mutant protein subcellular localization, and thereby investigated whether the haplotype variant of hMYH gene was associated with human colorectal carcinogenesis.
