As we all know, the pathological change of intestine induced by neutron irradiation is on the whole elucidated, while the mechanisms of injury were not elucidated completely.
However, the precise regulatory mechanisms of Kif4A-CCL2/CCR2-macrophage axis in this context have not been elucidated completely.
In addition, the mechanisms of chemical reactions involved are still not elucidated completely, so the process is difficult to control and represents a major challenge for food engineers.
The effects of mechanical deformation of intact cartilage tissue on chondrocyte biosynthesis in situ have been well documented, but the mechanotransduction pathways that regulate such phenomena have not been elucidated completely.
With the newly identified sequences further specific primers were designed and TAIL-PCR was conducted as described above until the gene sequences were elucidated completely.
The precise sequence of molecular events leading to recalcitrance to Bcr-Abl inhibitor therapy as well as the cellular framework in which they occur has not been elucidated completely.
A previous study [10] confirmed PAG dysfunction in migraine, and functional MRI studies demonstrated that the PAG dysfunction was associated with increased iron deposition, which may play a role in the genesis or pathophysiology of MOH [4, 11, 12] The PAG dysfunction changes might explain the neuromechanism of migraine, however, the PAG structure change was not elucidated completely.
In contrast to the plethora of information about mutations in the TGFβ signal cascade in colon, gastric and pancreatic cancers [2], [11] [13], the contribution of perturbed TGFβ signalling in oesophageal adenocarcinoma has not been elucidated completely.
Pathogenesis has not been elucidated completely, and disease-modifying treatment and prevention are presently not available.
However, mechanisms of initiation and progression of liver cancer have not been elucidated completely.
The pathogenesis and etiology of IA have not been elucidated completely.
