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A highly purified RNA polymerase II elongation control system.
Our analysis demonstrates that, over a wide range of physical parameters, increased speed and synchrony are functional consequences of elongation control.
While this effect does not seem to be related to elongation control, it has not been established by which mechanisms this region affects overall trancription.
If a mechanism similar to this type of elongation control exists in trypanosomes, it raises the intriguing possibility of RNAP-II transcriptional control, heretofore unrecognized, in these organisms.
Hence, it is tempting to speculate that the elongation control of gadd45b by Foggy/Spt5 is the switch that regulates these 'preset' genes.
Transcription elongation control of such 'preset' genes might be crucial to integrate signals from multiple pathways (gadd45b controlled by NF-kB and TGF-b) to coordinate regulation of important signaling pathways that ultimately determine cell fate and survival.
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Ductility improvement is attributed to the enhanced uniform elongation correlated with twinning suppression, and the enhanced post necking elongation controlled by grain refinement, especially at the fine grain sizes.
Among the four members, LARP7 is the only one that binds to 7SK snRNA and is involved in transcription elongation controlled by Pol II.
For Arabidopsis it has been shown that endosperm growth has a reciprocal effect on integument cell elongation to control final Arabidopsis seed size [ 37].
Gibberellic acid also regulates a diverse array of developmental processes such as seed development and germination, organ elongation and control of flowering time [ 62].
While at the translational level, the number of ribosomes (i.e., rRNA) and the availability and the state of activation of initiation and elongation factors control the rate of translation of mRNA into protein (Bolster et al. 2003).
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