These reactions afforded only aryl cyclobutene 4k′ via an elimination pathway (Supplementary Fig. 10, eq1).
The components were selected to influence the body elimination pathway upon nanocarrier biodegradation.
A better understanding of the genistein elimination pathway could shed light on such mechanisms.
In addition, the behaviour of the two main ibuprofen biodegradation intermediates (carboxy and hydroxy derivatives) supported that the main ibuprofen elimination pathway occurs in aerobic conditions.
We developed a Petri net model that represents this multi-organ elimination pathway and which assists in the design of future experiments.
Furthermore, the steric bulk of the PtBu3 ligand allows for a low-coordinate, dissociative pathway and facile reductive elimination over the competing, undesirable β-hydride elimination pathway.
Model analysis revealed that a two-step molecular elimination pathway exclusively led to the fuel decomposition under pyrolysis conditions, while in the premixed flame the fuel was consumed mainly by hydrogen abstractions from the secondary carbon atoms.
Rate coefficient changes based on recent recommendations from literature, and an additional concerted elimination pathway important at moderate to low temperatures are introduced to the resulting chemical mechanism, which improve the model predictions.
The same metabolite pattern in the radiochromatograms for the two different labelling protocols led us to assume that the elimination pathway does not involve the removal of the ethinyl group from EE2 molecule.
Higher uptake in liver for both dimers seems to indicate a different elimination pathway and kinetics.
These ratios are modulated by the different elimination pathway and kinetics of both tracers.
