Sentence examples for elimination of function from inspiring English sources

Using a combination of genetic mutations and RNAi assays, we show that reduction or elimination of function of 12 of the candidate RBP-encoding genes reveals a reduction in the number of dendritic termini in PVD neurons.

We observed an antibody dose-dependent elimination of cystatin C inhibitory activity, with full elimination of function achieved by a sample to antibody ratio of 2 1, by volume in a CSF sample that contained the highest amount of cystatin C protein as determined by ELISA (Table  2).

Targeted elimination of nAChR function in zebrafish can be achieved with tethered α-bungarotoxin, silencing synaptic transmission without perturbing synapse formation.

Moreover, the strong Sal upregulation and overgrowth caused by TkvQD expression in wild-type cells was compensated by elimination of dTIEG function [32].

Ectopic dTIEG expression promotes overproliferation whereas elimination of dTIEG function in cell clones using a null allele produces a failure in cell proliferation.

To determine the in vivo function of PiT1, we targeted the PiT1 locus by homologous recombination in ES cells and generated an allelic series of mutations ranging from mild impairment to elimination of PiT1 function.

In Drosophila, however, the elimination of dTIEG function did not cause detectable changes in the expression of either the I-Smad/Dad (data not shown) or Brk suggesting certain differences in the mechanism of action of dTIEG.

In contrast, the elimination of dTIEG function in somatic clones causes a down-regulation of sal and omb expression indicating a decrease of Dpp/BMP2 activity in the wing disc.

Since our approach, like previous studies [6], [10], [11], [21], relied upon DAT expression for the selective elimination of NMDAR function in DA neurons, we considered it important to determine whether NR1 gene deletion occurred in mesostriatal and mesocortical circuits, because the latter is characterized by DA neurons with low or undetectable DAT protein levels [12].

Strikingly, the elimination of eiger function completely abrogated the non-autonomous apoptosis in the anterior compartment.

This feature is important when studying biological phenomena resulting from down-regulation, but not elimination, of gene function.