First, the attempt to increase the CO2 elimination capability when using ECCO2R depends on two important parameters, which are not independent from each other: the blood flow rate and the membrane lung surface area.
At dose level 3, those patients with lower drug elimination capability develop dose-limiting toxicity and subsequently that dose level is defined as the maximum tolerated dose.
Pretreatment in vivo tests of genotype or phenotype will identify the estimated 20 to 30% of patients who fall into the extremes of drug elimination capability.
Consideration should be given to using fixed dose guidelines independent of body surface area and based on drug elimination capability, both as a starting dose and for dose adjustment, which may have accuracy, safety and financial advantages.
In addition to its flap adherence and potential space elimination capability, fibrin sealant is also an excellent blood clotting agent and can seal tissues to prevent lymphatic leak or serous fluid accumulation.
The most likely explanation for the origin of these kinetic differences is that goats have a greater metabolic capacity and elimination capability of ABZ-SO in comparison with sheep.
Apart from its superior error resilience capabilities, the elimination of multipoint control unit (MCU) in video conference systems leads to great reduction of deployment cost and transmission delay [2].
The self-elimination and self-replication capabilities of cell(s) are performed when the FTS detects a failure in any of the processors that include it, so that this cell(s) will be self-discarded for future implementations.
Phyllis Bennis (letter, Nov. 4) argues for the elimination of Israel's nuclear capability in order to achieve "real peace" in the Middle East.
Objective: To evaluate the capability of ICG elimination as a marker of development of graft dysfunction, kidney dysfunction or mortality.
