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This strategy was based on the principle that lowering (but not eliminating) the expression of a target gene using antisense technology would cause the bacteria to be more susceptible to an antimicrobial compound targeting the product of that gene.
Eliminating the expression of the male form of the neural sex determination factor, Fruitless (FruM), in three OA suboesophageal ganglia (SOG) neurons also leads to increased male-male courtship behavior in these same contexts.
Eliminating the expression of these genes has potential therapeutic utility for breast cancer.
This can be achieved by introducing novel genes or pathways, and/or enhancing or eliminating the expression of endogenous pathways.
We then further investigated the efficiency of c-Jun on the mesenchymal phenotype of KB/VCR cells by eliminating the expression of c-Jun with small RNA interference approach.
They show that light-mediated stimulation of those neurons entrains the respiratory rhythm whereas eliminating the expression of both transcription factors or reducing their synaptic transmission abolishes the respiratory chemoreflex.
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Short hairpin RNAs expressed by a lentiviral vector were used to eliminate the expression of all endogenous survivin isoforms, and an in vivo Bcl2 IP was performed on survivin-ΔEx3 positive- and negative-HeLa cell lysates.
TALENs were used to eliminate the expression of the endogenous TCR α and β chains to improve the expression and functionality of transgenic virus-specific TCRs (Berdien et al., 2014).
We find that FOXC2-KD in HMLE-Snail cells eliminates the expression of ZEB1, vimentin and fibronectin while it restores the expression of E-cadherin, thus inducing a complete MET irrespective of SNAIL overexpression (Fig. 6c).
One could have the genetic correlate of a trait and that trait could be the result of natural selection, and yet changing the environment could eliminate the expression of that trait.
The deletion of St6gal1 in mice eliminated the expression of the Sambucus nigra agglutinin (SNA) epitope [16], which is also recognized by SSA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com