Charge-neutralizing mutation of Asp3.32 in clade I TAARs, TAAR10a and TAAR12h, completely eliminated responses to serotonin and 2-phenylethylamine respectively, while charge-neutralizing mutation of Asp5.42 in clade III TAARs, TAAR16c and TAAR16f, completely eliminated responses to N-methylpiperidine and isoamylamine respectively.
In brief, this method eliminates reaction times over 10000 ms; however, since our task was a rapid forced-choice task, we eliminated responses with more than the 2000 ms from the analysis.
To prepare items for Round 2, the project team: (1) collated all Round 1 responses; (2) eliminated responses that were unclear (such as Program Integrity), unrelated to business ethics (such as Euthanasia in Europe or Genetic Testing), or redundant; and (3) identified major subject headings and subsumed specific topics under them.
Randomized response is an interview technique designed to eliminate response bias when sensitive questions are asked.
Surprisingly, while many fMRI researchers routinely take pains to eliminate response accuracy differences as a potential confound (e.g., by only analyzing trials with correct responses), relatively few studies have systematically controlled for trial-by-trial RT differences [e.g.], [5], [7,47]; a recent survey of 170 fMRI studies found that only 9% had explicitly modeled RT [3].
That included first eliminating response latencies for inaccurate trials.
pMCRE contains tandem ATF sites from the Mitf-M promoter placed upstream of the RSV TATA box and is activated by EWS/ATF1, while mutations that eliminate ATF1 binding (pMCREm) also eliminate response to EWS/ATF1.
Engineering the single SNP change in the marine enhancer (p3.2mar(T → G)- Luc) reduced but did not eliminate response to β-catenin in the heterologous system (28% lower expression with 50 ng of β-catenin, p < 0.001, n = 4).
This allowed us to eliminate response-related conflicts, which might occur between planning and execution of two successive motor responses even in our unspeeded design.
It should be noted that eliminating callosal input to primary visual areas does not eliminate responses to visual stimuli, suggesting that the callosal input has a modulatory, rather than strongly excitatory, effect.
