When fewer than five samples yielded undetectable metabolite levels, the logistic regression component of the mixture model was eliminated, yielding results consistent with straightforward linear models.
In particular, binding was eliminated by L366K, consistent with the results for Lgs [ 20], but only reduced by L363F (Fig. 1B).
In contrast to genomic DNA, best-fit models of dinucleotide frequencies in transcribed RNA sequences expressed in the cytoplasm from all organisms were dominated by mutations that eliminated UpA dinucleotides, observations consistent with cytoplasmically driven selection for mRNA stability.
In this study, we showed that substitution of AQP9 residue Arg-219 eliminates MAs III) uptake, consistent with a requirement for an arginine residue for conduction of CH3As(OH)2.
The finding that GSK3 reduced but did not eliminate apoptosis is also consistent with the direct effects of Akt on other proapoptotic effectors, including FOXO and Bad.
We also found that H3K27me3 was enriched in FT chromatin in Col as reported previously [39], and that H3K27me3 in FT was nearly eliminated in clf (Figure 6B), consistent with the drastic de-repression of FT in clf (Figure 3C).
The I375V mutation eliminated two connection domain resonances, consistent with the 3.4 Å separation of the δ-methyl groups of Ile375 and Ile329, indicating that Ile329 also experiences a major shift perturbation.
The overrepresentation of the retrogenes among the old retrocopies and decrease in frequency of relatively old retrocopies indicated that many of the retrocopies might have been eliminated during evolution, which was consistent with our predictions based on the expected lack of regulatory elements and introns in the retrocopies.
Consistent with this, eliminating in-flight transmission by wearing protective masks increases the delay only marginally.
Furthermore, increasing the value of the sparsity control parameter may decrease the number of prior connections by enforcing more sparsity and eliminating connections that are least consistent with the experimental data.
