These changes to protein dynamics may reshape access tunnels and active site binding pockets as well as accelerate or even eliminate rate-limiting conformational changes in the catalytic reaction cycle.
A withdraw time of more than 32 d was suggested based on the drug eliminating rate and pharmacokinetic model described by a polyexponential equation.
Data of mean residue time (MRT) and body clearance (CLz) indicated that both enrofloxacin and its metabolite ciprofloxacin present similar eliminating rate and pattern in serum, muscle and liver.
The methods demonstrated here are applicable for identifying and eliminating rate-limiting steps in other constructed biosynthetic pathways.
This stepwise approach of sequentially eliminating rate-limiting processes can be used to identify possible means of performance enhancement in a broad range of applications.
Moreover, it also uses the signal indicator SNR from ACK frames to infer the signal quality at the receiver, eliminating rates that definitely cannot improve performance and allowing quick adaptation in unstable environments.
This problem cropped up in Thailand, where a fixed exchange rate appeared to eliminate exchange-rate risk, encouraging a lending boom.
In addition, the tail-biting technique has been widely used in convolutional encoders to eliminate the rate loss caused by the known tail bits.
During your end-of-day reflection, don't forget to write what you wish to cultivate and eliminate, and rate your day.
All measurements of P-R interval used to assess atrioventricular conduction were made during pacing to eliminate heart rate dependent changes in this variable.
This approach was used to eliminate growth rate differences between the Avicel, CMC and Miscanthus-grown cultures, as well as any conidial germination differences, such as those previously reported for N. crassa grown in Avicel versus Miscanthus media [ 8].
